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Xeljanz

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What Is Xeljanz?

Xeljanz, also known as tofacitinib, is an FDA-approved prescription medication that is commonly used to treat individuals diagnosed with moderate to severe rheumatoid arthritis (RA) or active psoriatic arthritis (PsA). This medication belongs to a class of drugs known as Janus kinase (JAK) inhibitors. It works by inhibiting certain enzymes in the body that are involved in the immune response, reducing inflammation and relieving symptoms associated with these forms of arthritis. Xeljanz is available in tablet form and is typically taken orally, with or without food. The dosage and duration of treatment will depend on the individual's specific condition and the guidance of their healthcare provider. It's important to note that Xeljanz may have potential side effects, such as increased risk of infections, changes in blood cell counts, liver problems, and an increased risk of certain cancers. It is crucial for patients to discuss any existing medical conditions and medications with their healthcare provider before starting Xeljanz treatment. As with any prescription medication, it is important to follow the instructions of your healthcare provider and report any concerning side effects or issues during treatment. A healthcare professional can provide specific guidance and answer any additional questions about Xeljanz.

How to use Xeljanz?

Xeljanz, also known as tofacitinib, is a prescription medication that is used to treat moderate to severe rheumatoid arthritis and active psoriatic arthritis. It is available in tablet form and is typically taken by mouth. The specific dosing instructions for Xeljanz can vary depending on the individual's condition and their response to the treatment. It is important to follow your doctor's instructions and the dosage prescribed on the medication label. Typically, the recommended starting dose for Xeljanz in adults with rheumatoid arthritis is 5 mg twice daily. For individuals with psoriatic arthritis, the usual starting dose is 5 mg twice daily or 11 mg once daily, depending on the severity of the condition. It is generally recommended to take Xeljanz with or without food. However, if you experience stomach upset, taking it with food may help alleviate these symptoms. Xeljanz should be taken regularly as prescribed by your doctor. It may take some time before you start experiencing the full benefits of the medication. Do not stop or change the dosage without consulting your doctor, as this can affect the effectiveness of the treatment. If you have any questions or concerns about how to use Xeljanz, it is important to discuss them with your healthcare provider. They can provide you with specific instructions tailored to your individual needs and medical condition.

The use of Xeljanz (tofacitinib) is associated with certain warnings and precautions that users should be aware of. These include: 1. Serious Infections: Xeljanz can increase the risk of serious infections, including bacterial, viral, fungal, and tuberculosis infections. Users should be vigilant for any signs of infection such as fever, cough, or persistent illness and immediately report them to their healthcare provider. 2. Lymphoma and Other Cancers: There have been cases of lymphoma and other malignancies reported in patients taking Xeljanz. Individuals with a history of cancer should discuss the risks and benefits of Xeljanz with their doctor before starting the medication. 3. Blood Clots: Xeljanz can increase the risk of blood clots in veins, which may lead to deep vein thrombosis or pulmonary embolism. Users with a history of blood clots or those at increased risk should inform their healthcare provider. 4. Thrombocytopenia: Xeljanz may cause a decrease in platelet count in some individuals. Regular blood tests may be necessary to monitor platelet levels during treatment. 5. Gastrointestinal Perforations: Xeljanz has been associated with gastrointestinal perforations, especially in individuals with a history of diverticulitis. Users should promptly report any abdominal pain, fever, or signs of peritonitis to their doctor. 6. Liver Enzyme Abnormalities: Xeljanz can cause changes in liver enzyme levels. Regular monitoring of liver function through blood tests is typically recommended during treatment. 7. Immunosuppression: Xeljanz can suppress the immune system, increasing the risk of infections. Individuals with chronic or recurring infections should consult their healthcare provider before starting Xeljanz. It is crucial for users to thoroughly discuss potential risks and benefits with their healthcare provider before starting Xeljanz and to promptly report any concerning symptoms or side effects during treatment.

Before taking Xeljanz, it is essential to be aware of the following warnings and precautions: 1. Infections: Xeljanz can increase the risk of infections, including serious and potentially life-threatening ones. If you have a history of chronic infection or are prone to recurrent infections, caution should be exercised. It is crucial to inform your healthcare provider about any signs or symptoms of infection, such as fever, cough, or flu-like symptoms. 2. Tuberculosis (TB): Xeljanz may increase the risk of developing TB or reactivating latent TB. Prior to starting treatment, a healthcare professional should evaluate you for TB infection. If you have an active or latent TB infection, appropriate treatment should be initiated before initiating Xeljanz. 3. Malignancies: There have been reports of an increased risk of certain types of cancer, such as lymphoma and lung cancer, with the use of Xeljanz. Individuals with a history of cancer or those who are at risk should discuss the potential benefits and risks of Xeljanz with their healthcare provider. 4. Blood Clots: Xeljanz has been associated with an increased risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism (PE). If you have a history of blood clots or are at risk for developing them, your healthcare provider will need to carefully evaluate the benefits and risks of Xeljanz in your individual case. 5. Gastrointestinal Perforations: Rare cases of gastrointestinal perforations have been reported with the use of Xeljanz. If you experience abdominal pain, fever, or severe gastrointestinal symptoms, seek immediate medical attention. 6. Hepatitis B Virus Reactivation: Xeljanz has been associated with the reactivation of hepatitis B virus in individuals who are chronic carriers of this virus. Prior to initiating treatment, your doctor may perform tests to determine your hepatitis B status. It is crucial to discuss your medical history, current medications, and any concerns with your healthcare provider before starting Xeljanz. They will be able to assess the risks and benefits of this medication specifically for you.

Xeljanz (tofacitinib) is a prescription medication primarily used to treat moderate to severe rheumatoid arthritis and active psoriatic arthritis in adults. While it can be effective in managing these conditions, it is important to be aware of potential side effects that may occur with its use. Common side effects of Xeljanz may include upper respiratory tract infections, headache, diarrhea, nasal congestion, and sore throat. Other side effects that have been reported include stomach discomfort, nausea, elevated cholesterol levels, increased liver enzymes, and decreased blood cell counts. It is worth noting that Xeljanz may weaken the immune system, making individuals more susceptible to infections. Therefore, it is crucial to promptly report any signs of infection, such as fever, cough, or skin redness, to a healthcare professional. In rare cases, Xeljanz has been associated with serious side effects, including blood clots, lung infections, and certain types of cancer, such as lymphoma. Therefore, it is important to inform your doctor about any pre-existing medical conditions, such as a history of blood clots or cancer, before starting Xeljanz. Due to the risks associated with this medication, regular monitoring of blood cell counts, liver function, and cholesterol levels may be necessary during treatment. Overall, it is vital to have open and frequent communication with your doctor regarding any potential side effects or concerns while taking Xeljanz. They can provide personalized guidance and help weigh the benefits against the risks to ensure the best possible treatment outcomes.

The active ingredient in Xeljanz is tofacitinib citrate. Tofacitinib citrate is an oral medication that belongs to a class of drugs known as Janus kinase (JAK) inhibitors. In addition to tofacitinib citrate, Xeljanz also contains inactive ingredients like croscarmellose sodium, lactose monohydrate, magnesium stearate, and sodium phosphate dibasic anhydrous. It's important to note that Xeljanz is a prescription medication and should only be used under the guidance and supervision of a healthcare professional. This medication helps reduce symptoms associated with rheumatoid arthritis or psoriatic arthritis, such as joint pain, swelling, and stiffness. However, it does come with potential side effects and should be taken as directed by a healthcare provider. Always consult with your doctor or healthcare professional for personalized information regarding Xeljanz and its ingredients.

Xeljanz, also known as tofacitinib, is a prescription medication primarily used for treating moderate to severe rheumatoid arthritis and active psoriatic arthritis. When it comes to storing Xeljanz, it's essential to follow the manufacturer's recommendations and your healthcare provider's instructions. Typically, Xeljanz should be stored at room temperature, away from excessive heat or cold. It is important to keep the medication in its original container, tightly closed, and out of reach of children or pets. Avoid exposing Xeljanz to direct sunlight, moisture, or extreme temperatures. Additionally, it's crucial to check the expiration date on the medication and discard any expired or unused tablets. If you have any concerns or questions about how to store Xeljanz, it's best to consult your healthcare provider or pharmacist for specific guidance. They can provide you with the most accurate and up-to-date information regarding the storage requirements of this medication.