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Trulance

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What Is Trulance?

Trulance is a brand-name tablet that has been approved by the FDA for the treatment of specific bowel problems, namely chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). It belongs to a class of medications called guanylate cyclase-C agonists. This medication works by increasing the levels of fluid in the intestines and promoting bowel movements, which helps alleviate symptoms such as difficulty passing stools, infrequent bowel movements, and abdominal discomfort associated with CIC and IBS-C. Trulance acts locally in the intestines and does not get absorbed into the bloodstream in significant amounts. It is important to follow the prescribed dosage and any instructions provided by your healthcare provider when taking Trulance. Like any medication, Trulance may cause side effects, including diarrhea, abdominal pain, and gas. It is always advisable to consult with a healthcare professional regarding the appropriate use of Trulance and to discuss any potential risks or concerns.

How to use Trulance?

To use Trulance, it is important to follow the instructions provided by your healthcare provider and the medication's label. Here are some general guidelines for using Trulance, though please consult your doctor for personalized advice: 1. Take Trulance exactly as prescribed by your doctor. Your dosage may be different depending on your specific condition and medical history. 2. Trulance is typically taken by mouth, with or without food. Follow your doctor's instructions regarding timing and whether it should be taken on an empty stomach. 3. Swallow the tablet whole with water. Do not crush, chew, or break it. 4. The recommended starting dose for treating chronic idiopathic constipation (CIC) is 3 mg per day. Your doctor may adjust this dosage based on your response and tolerance. 5. For patients with irritable bowel syndrome with constipation (IBS-C), the recommended starting dose is 3 mg per day. If needed, your doctor may increase the dose to 6 mg per day. 6. It is important to take Trulance consistently at the same time each day to help establish a routine. 7. If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. 8. It may take some time before Trulance starts to work effectively. Be patient and continue taking it as prescribed, even if you don't see immediate results. If you have any concerns about the medication's effectiveness, consult your doctor. Remember, this is just a general guide. Always consult your doctor or pharmacist for complete and personalized instructions on how to use Trulance based on your specific needs and medical condition.

There are several warnings associated with the use of Trulance (plecanatide). This medication is an FDA-approved brand-name tablet prescribed for the treatment of certain types of bowel problems, specifically chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). It's important to note that Trulance is not recommended for patients under the age of 18. Additionally, if you have a blockage in your intestines or a history of bowel obstruction, you should not use this medication. Trulance may cause diarrhea, which can sometimes be severe. If you experience severe diarrhea or symptoms of dehydration, such as dizziness or decreased urination, it is essential to seek medical attention. Other warnings associated with Trulance include the potential for allergic reactions, including rash, itching, swelling, and difficulty breathing. If you experience these symptoms, it is important to discontinue the medication and seek immediate medical assistance. As with any medication, it's crucial to inform your healthcare provider about any other medical conditions you have and any medications or supplements you are currently taking. They can provide appropriate guidance and ensure Trulance is safe for you to use. It's also essential to follow the prescribed dosage and instructions provided by your healthcare provider. If you have any questions or concerns about the use of Trulance, make sure to discuss them with your healthcare provider for clarification and guidance.

Before taking Trulance, it is crucial to be aware of certain warnings and precautions associated with the medication. These include: 1. Allergic reactions: If you have a known allergy to Trulance or any of its ingredients, it is important to avoid taking this medication. Signs of an allergic reaction may include hives, difficulty breathing, swelling of the face, lips, tongue, or throat. Seek immediate medical attention if you experience these symptoms. 2. Gastrointestinal obstruction: Trulance should not be used if you have known or suspected gastrointestinal obstruction, as it may worsen the condition. It is important to inform your healthcare provider if you have a history of any gastrointestinal disorders before starting this medication. 3. Severe diarrhea: Trulance can cause diarrhea, which may be severe in some cases. If you experience persistent or severe diarrhea while taking Trulance, contact your healthcare provider. Dehydration and electrolyte imbalances may occur with prolonged or excessive diarrhea. 4. Pediatric use: Trulance is not recommended for use in children under 6 years of age. Safety and effectiveness in pediatric populations have not been established for the treatment of chronic idiopathic constipation (CIC) or irritable bowel syndrome with constipation (IBS-C). 5. Pregnancy and breastfeeding: It is important to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before taking Trulance. The effects of Trulance on pregnancy and breastfeeding are not fully understood, and your healthcare provider will weigh the potential benefits and risks before recommending its use. It is essential to follow your healthcare provider's instructions and discuss any concerns or questions regarding Trulance before initiating treatment. Always inform your healthcare provider about any other medications, vitamins, or supplements you are taking, as they may interact with Trulance and affect its effectiveness or safety.

Trulance (plecanatide) is an FDA-approved medication used for the treatment of certain types of bowel problems, including chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). As with any medication, Trulance may cause certain side effects. It's important to note that not everyone will experience these side effects, and some individuals may experience different effects than others. Common side effects of Trulance include diarrhea, stomach pain, gas, bloating, and headache. These side effects are generally mild and tend to improve over time. It is advisable to consult a healthcare professional if these side effects persist or become bothersome. In rare cases, severe diarrhea, sometimes accompanied by dehydration or electrolyte imbalances, has been reported. If you experience persistent or severe diarrhea while taking Trulance, it is important to notify your healthcare provider. As always, it's crucial to follow your doctor's instructions and report any side effects or concerns that arise while taking Trulance. Medical professionals are well-equipped to provide guidance and assistance in managing any adverse effects that may occur.

The active ingredient in Trulance is plecanatide, which is a synthetic analog of a naturally occurring human peptide called uroguanylin. Uroguanylin is involved in regulating fluid balance in the intestine and enhancing bowel movements. Trulance also contains other inactive ingredients, which include lactose monohydrate, microcrystalline cellulose, citric acid monohydrate, croscarmellose sodium, sodium bicarbonate, magnesium stearate, and talc. These ingredients help to bind the active ingredient, form the tablet, and improve its stability and absorption in the body. It's worth noting that individuals who have allergies or sensitivities to any of the ingredients in Trulance should avoid taking this medication. It's always important to read the drug's label and consult with a healthcare professional to ensure its suitability and safety for you.

Trulance, an FDA-approved brand-name tablet, is used for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). When it comes to the storage of Trulance, it is essential to follow the manufacturer's recommendations for proper handling and storage to ensure its effectiveness and safety. The medication should be stored at room temperature, typically between 68°F to 77°F (20°C to 25°C). It is important to keep Trulance in its original container, ensuring that it is tightly closed and protected from moisture, heat, and direct sunlight. Avoid exposing the medication to extreme temperatures or humidity. As with any medication, it is crucial to store Trulance out of reach of children and pets to prevent accidental ingestion. It is recommended to keep it in a secure location, away from areas where it can be easily accessed. If you have any specific concerns about the storage of Trulance or any medication, it is always best to consult with your healthcare provider or pharmacist for detailed instructions and guidance. They can provide you with personalized advice based on your individual circumstances.