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Arixtra

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What Is Arixtra?

Arixtra, also known by its generic name fondaparinux, is a medication that is primarily used to prevent blood clots in patients who have undergone hip, knee, or abdominal surgery. It belongs to a class of drugs called anticoagulants, or blood thinners. After surgery, there is a heightened risk of blood clots forming, which can be dangerous if they travel to vital organs such as the lungs or brain. Arixtra works by inhibiting a substance in the blood called factor Xa, which plays a crucial role in blood clot formation. By blocking this substance, Arixtra helps to prevent the formation of blood clots and reduces the risk of serious complications such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Arixtra is typically administered as a subcutaneous injection, meaning it is injected just under the skin. The dosage and duration of treatment will vary depending on the specific surgical procedure and the patient's individual risk factors. It's important to note that Arixtra is a prescription medication and should only be used under the guidance and supervision of a healthcare professional. Like all medications, Arixtra can have side effects, including bleeding, bruising, and allergic reactions. It's crucial for patients to discuss any potential risks or concerns with their doctor before starting this treatment.

How to use Arixtra?

Arixtra, the brand name for the medication fondaparinux, is an injectable anticoagulant used to prevent blood clots in patients who have undergone hip, knee, or abdominal surgery. Here is a general guideline on how to use Arixtra: 1. A healthcare professional will administer Arixtra via subcutaneous injection, usually in the fatty tissue of the abdomen. 2. Follow the dosage and schedule prescribed by your doctor. The dose may vary depending on factors such as the type of surgery and your body weight. 3. Arixtra is typically given once daily, and the duration of treatment will be determined by your doctor. 4. To ensure the sterility of the injection, the healthcare professional will use a new needle and syringe for each dose. 5. It is important to avoid any sudden stops or changes in the dosage without consulting your doctor. It is essential to inform your doctor about any existing medical conditions, such as an increased risk of bleeding, liver or kidney problems, or any other medications you are taking, as they may affect the use of Arixtra. Additionally, if you experience any unusual symptoms or side effects, contact your healthcare provider immediately.

Before using Arixtra (fondaparinux), it's important to be aware of certain warnings associated with its use. It's a prescription injection that is approved by the FDA for the prevention of blood clots in patients undergoing hip, knee, or abdominal surgery. One of the main warnings with Arixtra is the risk of bleeding. This medication can increase the risk of bleeding, which can be serious or even life-threatening in some cases. It's crucial to inform your healthcare provider if you have any conditions that may increase your risk of bleeding, such as a history of bleeding disorders, recent surgery, or organ damage. Another important warning is the risk of spinal or epidural hematoma. Arixtra should not be used in patients who are receiving anesthesia through the spinal or epidural route or within 6 to 8 hours after removal of the epidural catheter, as it may increase the risk of developing a blood clot in the spine, which can lead to paralysis. Other warnings include the increased risk of thrombocytopenia (low platelet count) and the need for regular monitoring of kidney function in individuals with impaired renal function. It is essential to follow the recommendations and instructions provided by your healthcare provider and report any unusual symptoms or side effects while using Arixtra.

Before taking Arixtra (fondaparinux), there are several important warnings to be aware of: 1. Bleeding risk: Arixtra is an anticoagulant medication, which means it can increase the risk of bleeding. This includes the risk of serious or life-threatening bleeding. It is crucial to inform your healthcare provider if you have any bleeding disorders, a history of stroke or bleeding in the brain, recent surgery or trauma, or if you are taking other medications that increase the risk of bleeding. 2. Spinal or epidural blood clots: Arixtra should not be used in patients who are receiving or have received spinal or epidural anesthesia, or who have a spinal puncture. This is because it can increase the risk of developing blood clots in the spinal cord, which can lead to paralysis. If you are undergoing or have recently undergone any procedures involving spinal or epidural anesthesia, it is important to inform your healthcare provider. 3. Kidney function: Arixtra is primarily eliminated from the body through the kidneys. Therefore, it is essential to inform your healthcare provider if you have any kidney problems or if you are undergoing dialysis. Your dosage may need to be adjusted accordingly. 4. Other medical conditions: It is essential to inform your healthcare provider about any other medical conditions you have, including liver disease, high blood pressure, ulcers, or a history of bleeding disorders. Arixtra should be used with caution in these situations. 5. Pregnancy and breastfeeding: The use of Arixtra during pregnancy or breastfeeding should be discussed with your healthcare provider. It is important to weigh the potential benefits against the potential risks, as the medication may pass into breast milk and can affect the baby. It is crucial to closely follow your healthcare provider's instructions and communicate any concerns or side effects. Arixtra is a prescription medication that should only be used under the supervision and guidance of a healthcare professional.

Some of the potential side effects of Arixtra (fondaparinux) include: 1. Bleeding: As Arixtra is an anticoagulant (blood thinner), it can increase the risk of bleeding. This may manifest as prolonged bleeding from wounds, easy bruising, nosebleeds, bleeding gums, or blood in the urine or stools. It's important to promptly notify your healthcare provider if you experience any unusual bleeding. 2. Injection site reactions: Some individuals may experience mild to moderate pain, swelling, or bruising at the site of injection. These reactions are usually temporary and resolve on their own. 3. Allergic reactions: Although rare, allergic reactions to Arixtra can occur. Symptoms may include rash, itching, swelling, dizziness, or difficulty breathing. If you experience any signs of an allergic reaction, seek immediate medical attention. 4. Thrombocytopenia: A rare but serious side effect of Arixtra is a decrease in platelet count, known as thrombocytopenia. This can lead to an increased risk of bleeding. Regular blood tests may be required to monitor platelet levels during treatment. It's essential to discuss all potential risks and side effects with your healthcare provider before starting Arixtra. They will be able to provide personalized guidance and monitor your response to the medication closely.

The main active ingredient in Arixtra is fondaparinux sodium, a synthetic anticoagulant. It belongs to a class of medications called selective factor Xa inhibitors. Other ingredients in the injection include sodium chloride, water for injection, and, depending on the specific formulation, may also include small amounts of other compounds for pH adjustment. Fondaparinux works by inhibiting the activity of factor Xa, a protein involved in the blood clotting process. By preventing the formation of blood clots, Arixtra helps reduce the risk of deep vein thrombosis (DVT), pulmonary embolism (PE), and other clot-related complications in patients undergoing hip, knee, or abdominal surgery. It's important to note that this medication should only be used under the guidance and prescription of a healthcare professional, as it may have potential side effects and drug interactions.

Arixtra (fondaparinux) is a prescription injection that is used to prevent blood clots in patients who have undergone hip, knee, or abdominal surgery. Proper storage of Arixtra is important to maintain its effectiveness and ensure patient safety. Arixtra should be stored at room temperature, ideally between 68°F to 77°F (20°C to 25°C). It should be kept in its original packaging, away from moisture and direct sunlight. It is essential to store Arixtra out of reach of children and pets. It is important not to freeze Arixtra as freezing can damage the medication and render it ineffective. If the medication is accidentally frozen, it should be discarded and not used. Additionally, it is important to check the expiration date of Arixtra before using it. Expired medication may not work as intended and should be safely disposed of. If you have any doubts or questions regarding the storage of Arixtra, it is always best to consult with your healthcare provider or pharmacist for specific storage instructions based on your individual circumstances.

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